طب اورژانس

 Which of the following is true regarding therapeutic hypothermia in comatose survivors of cardiac arrest?

      1: Prolonged pharmacologically induced paralysis is often required to control shivering.

      2: Pregnancy is an absolute contraindication.

      3: To achieve benefit, the target temperature must be reached in less than 30 minutes.

      4: Gradual rewarming should occur over 4 hours.

      5: Target core body temperature should be 32° C to 34° C.